The Bubble Poppin' Boys are chasing after SpongeBob. The player uses the space bar to blow bubbles at them and trap them. When they are in a bubble, the player jumps on the bubble to get rid of them and picks up the bonus item they drop. When the player gets rid of all the Bubble Poppin' Boys, the player moves on to the next level.
The green fish walks normally, the orange fish falls off ledges and jump, the purple fish chases SpongeBob when he sees him, and the red fish jumps and falls off ledges, and may also drop a Best Friends Forever half.
A Best Friends Forever power-up is powerful; If two Best Friends Forever halves are collected, All Bubble Poppin' Boys on the level get trapped inside bubbles. It is important to note that falling into a hole makes the player reappear at the top, and the Bubble Poppin' Boys will escape from a bubble after a period of time.
There are also lives. If SpongeBob bumps into a Bubble Poppin' Boy, he loses a life. If SpongeBob loses all of his lives, he falls off the screen, and the game ends.