Episodes in which they are prominent
- "Help Wanted" - Naked, SpongeBob jumps from his bed's diving board to his pants holder to put them on.
- "Plankton!" - While under the manipulation of Plankton, SpongeBob walks to his pants holder to put them on, only for him to slide under them and say "I guess I won't be wearing any pants today."
- "Boating School" - Patrick wears them throughout most of the episode.
- "F.U.N." - Plankton wears a much smaller version of these pants after playing with SpongeBob.
- "Hooky" - SpongeBob is forced to remove his pants due to being hooked, followed by his underwear too, much to his embarrassment.
- "Procrastination" - SpongeBob's pants come to life and run away from him during his dream sequence, yelling "Freedom!"
- "Rock-a-Bye Bivalve" – SpongeBob uses his pants as a temporary cradle.
- "Missing Identity" - SpongeBob tells the story of how a backwards-worn "shirt" of his caused him to lose his identity.
- "The Sponge Who Could Fly" - The inflation of his pants from a hair dryer causes SpongeBob to fly and become a hero to Bikini Bottom.
- "SpongeBob Meets the Strangler" - SpongeBob takes a pair of them to the dry cleaners during the montage of him and the Tattletale Strangler running errands.
- "Pranks a Lot" - SpongeBob and Patrick are forced to remove their pants to prevent the Invisible Spray from staining their clothes.
- "SquidBob TentaclePants" - SpongeBob's tie winks at him.
- "To SquarePants or Not to SquarePants" - SpongeBob is forced to buy a pair of round pants, due to his dryer shrinking those of the square variety.
- "A Day Without Tears" - SpongeBob rips a pair of them, causing him to burst into tears because it was his favorite "shirt."
- "SpongeBob LongPants" - SpongeBob's personality changes after he abandons his usual pants in favor of a pair of long pants.
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