SpongeBob and Patrick each get slide whistles and start playing them everywhere, even outside of Squidward's house, much to his annoyance. The two then start to use them for sound effects for everything Squidward does. He eventually has had enough and then flees out his house. This leads to SpongeBob and Patrick following him, thinking that he is finally playing with them.
Squidward, fed up, forcefully grabs SpongeBob's slide whistle and uses it against him and Patrick. Afterwards, Squidward becomes addicted to the instrument and irritates all of the Bikini Bottomites with his slide whistle. Soon enough, Squidward encounters a cliff and ends up falling off it.
He is then sent to the Bikini Bottom Hospital, with the slide whistle stuck in his throat. Since no one has the technology to remove it, they leave it on Squidward. SpongeBob and Patrick are then seen playing around with the slide whistle in the hospital as the episode comes to an end.