Encyclopedia SpongeBobia


Encyclopedia SpongeBobia
Encyclopedia SpongeBobia

"Single Cell Anniversary" is a SpongeBob SquarePants episode from season 6. In this episode, SpongeBob helps Plankton find an anniversary gift for Karen.



Single Cell Anniversary 003

Plankton walks to the Chum Bucket stinking with the stench of "failure," as he calls it, and Karen is in a very happy mood. Karen then smells Plankton and gives him a bath, taking off his skin, which is revealed to be his clothes. After he has washed, Plankton learns that it was his and Karen's wedding anniversary and that Karen got him a copy of the Krabby Patty secret formula for his present, but he cannot have it until he gets her a present.

Plankton is crying on the road and SpongeBob hears him crying. He sniffs like a dog and soon runs into Plankton. He tells SpongeBob the news, and SpongeBob yells to all of Bikini Bottom that there is a "Love Emergency." SpongeBob then tells Plankton that his present has to come from the heart, and he suggests a serenade. Plankton then remarks that he cannot sing, and SpongeBob takes him to the pineapple and works on Plankton's vocal cords. Plankton sings so high that he breaks the glass Squidward was drinking out of his juice and Sandy's helmet breaks while she was walking, then she runs back to her treedome for air. Then, Plankton goes off to serenade Karen.

Single Cell Anniversary 147

Plankton walks into the Chum Bucket and starts singing "Oh, My Karen," a mariachi-style song, and SpongeBob and Patrick play guitars in the background, wearing Mexican-style clothing and mustaches. Plankton also shakes maracas. Karen cries when it is over, and then she starts uploading the Krabby Patty secret formula; Plankton then tells SpongeBob that by wooing his computer wife, he has doomed the Krusty Krab and put said restaurant in grave peril. SpongeBob is shocked at this, so he unplugs what he thinks is Karen, but was just the coffee maker. Karen finally uploads the formula, but she starts crying again, and she breaks down and shorts out, leaving Plankton still without the secret formula, making him confused. She then shuts down, and the E.M.I.L.P. (Emergency Mother-In-Law Program) uploads and starts nagging, saying that Karen could have married the ATM, someone with money, as the episode ends.





 ) Production music
 ) Original music
 ) SpongeBob music

  Wahini Wobble Faster - Nicolas Carr, Sage Guyton, Jeremy Wakefield [title card]
  Emotion Blues - Francois Fournet, Eric Gemsa [Plankton comes home]
  Hawaiian Cocktail - Richard Myhill ["And now the smell of defeat so deeply penetrates my soul..."]
  Darting Around - Harry Bluestone [Karen cleaning Plankton]
  Steel Licks 78 - Jeremy Wakefield ["It's not enough to mask the ugliness I feel inside."]
  Darting Around - Harry Bluestone ["Did I miss a spot?"]
  Tension Bits - Nicolas Carr, Sage Guyton, Jeremy Wakefield [Plankton gets angry]
  Fantasy Princess [#52] - Harry Bluestone, Emil Cadkin ["It has something to do with you asking a certain someone..."]
  New Vibe Hits - Nicolas Carr ["What?"]
  Wedding Sting - Nicolas Carr ["We each wear rings in memory of this moment."]
  Steel Licks 22 - Jeremy Wakefield ["It's our wedding anniversary!"]
  Parting of the Clouds Sting - Nicolas Carr [Karen got Plankton the secret formula]
  SpongeBob Flashback Vibes - Nicolas Carr [start of flashback]
  Happy Sack Shanty - Michael Bolger, Nicolas Carr [Karen explains how she got it through a flashback]
  SpongeBob Flashback Vibes - Nicolas Carr [end of flashback]
  Romancing the Bottle - Nicolas Carr [Plankton kissing the formula bottle]
  Steel Licks 51 - Jeremy Wakefield [Karen wants a gift from Plankton]
  Hello Blues - Sage Guyton, Jeremy Wakefield ["And that's how I got my head stuck in the fry vat."]
  Accusation - Gerhard Trede [Plankton groaning]
  New Vibe Hits - Nicolas Carr ["Plankton?"]
  Hawaiian Cocktail - Richard Myhill [Plankton tells SpongeBob about his wedding anniversary]
  Chasey Racey - Norman Dane [love emergency]
  Goofy Conversation - Nicolas Carr, Barry Anthony ["There's only one thing to do."]
  Sport Fanfare - Gerhard Trede ["That's it!"]
  Goofy Conversation Continued Thin Mix - Nicolas Carr, Barry Anthony [Plankton telling SpongeBob about Karen]
  Lap Steel - Nicolas Carr [Transition to next scene]
  Sandys Threat - Nicolas Carr [Sandy's helmet breaks]
  Climb To Altitude - Trevor Duncan ["Oh, you are ready!"]
  Tiki Rapido - Lionel Wendling ["This is it, Plankton."]
  Ahhh Luve - Nicolas Carr ["Ah, love."]
  Lonely Heart's Club - David Bell, Otto Sieben [Plankton returns home]
  Oh, My Karen - Luke Brookshier, Eban Schletter [Plankton sings this]
  South Pacific Island II - Victor Cavini ["That was so beautiful!"]
  Crime And Danger Sign #3 - Delle Haensch, Hans Conzelmann ["The Krabby Patty formula?!"]
  Dramatic Sea Battle - Gerhard Trede ["I am so fired."]
  Victory Of Love - Gerhard Trede [Karen crying]
  Steel Licks 54 - Jeremy Wakefield [computer shorts out]
  Skipping to School - Sage Guyton, Jeremy Wakefield [Emergency Mother-In-Law Program]



"Kind of obscure, but one of the few episodes to focus on the "Honeymooners-like" marriage of Plankton and Karen (just a microorganism and his computer wife tryin' to get by). I love how Plankton swings between henpecked husband and world-conquering megalomaniac."



  • The episode's title is a pun on Sickle Cell Anemia.
  • This episode was available on The Tom Kenny Collection digital collection released in 2009, over one month before it aired on television.
  • This episode was going to be named "Green Anniversary."[1][2]
  • This episode was paired up with a rerun of "Pineapple Fever,"[3] but since it has re-airing with "Chum Bucket Supreme."
  • This was the third episode to premiere during Nickelodeon's "Deep Sea Danger Zone" marathon.
  • This episode reveals that Karen is a Mark II Surplus UNIVAC with 256 gigabytes of RAM.
  • SpongeBob knows what butterflies are in this episode, but not in "Wormy."
  • In "Enemy In-Law," Plankton says that he bought Karen. Yet in this episode during the "Oh, My Karen" song, he says that he built her.
  • On the Complete Sixth Season, The Best 200 Episodes Ever, and Season 6 Volume 2 DVDs, this was listed as the final episode of season 6. While it is not the last season 6 episode in airing order, it is the last in production order (prod. #193-652).
  • In the SpongeBob SquigglePants nanogame "Yes We Karen," Karen's face after the switches are flipped is from this episode.
  • In this episode, Plankton says he does not know how to sing, but he sings in 'F.U.N.," "Christmas Who?," and "Atlantis SquarePantis."


  • SpongeBob wears a mustache during the "Oh, My Karen" song, but when everyone else says, "Awww...," he no longer has a mustache.
  • When SpongeBob attempts to Ctrl-Alt-Del Karen, the keyboard keys are white. When Karen begins to short circuit, they are red.
  • At the beginning of the episode, Karen has the secret formula printed out in a bottle. However, at the end, Karen had to print it out.
  • When the camera zooms out of the Chum Bucket in the end, the pathway to the Krusty Krab is missing.



If Plankton and Karen Had Their Own Sitcom 👁❤️📺 - "Oh My, Karen!" Episode 1 - SpongeBob